If you’re on the Internet at all, you’ve almost certainly heard of semaglutide in its more common name-brand forms: Ozempic®, Wegovy®, and/or Rybelsus®. 

Semaglutide is a medication that belongs to the class of drugs known as GLP-1 (glucagon-like peptide-1) receptor agonists. It mimics the action of a naturally occurring hormone, GLP-1, which regulates blood sugar, insulin production, and appetite. 

Initially approved for managing type 2 diabetes, semaglutide has gained popularity in recent years for its significant weight-loss benefits, especially for individuals who are overweight. 

When coupled with exercise, this combination creates a powerful strategy to improve overall health, enhance weight loss, and manage chronic conditions. So, how do the two complement each other? Let’s dive in! 

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How does semaglutide work?

Semaglutide helps lower blood sugar levels by increasing insulin secretion and reducing glucose production by the liver. It also slows the emptying of the stomach, leading to increased satiety and reduced food intake. This dual action makes semaglutide an effective treatment not only for diabetes but also for obesity — a condition often tied to insulin resistance and metabolic dysfunction.

But semaglutide does more than just curb appetite. It positively impacts metabolic markers like cholesterol levels and blood pressure, making it an all-around powerful tool for managing chronic diseases. However, as with any medication, semaglutide works best when complemented by lifestyle changes, such as diet and exercise.

How do weight-loss medications and exercise work together?

We all know that exercise is one of the most effective ways to maintain overall health. Regular physical activity improves cardiovascular fitness, strengthens muscles, and enhances mental well-being. For individuals with type 2 diabetes or obesity, exercise also plays a critical role in improving insulin sensitivity, controlling blood sugar levels, and promoting weight loss.

Together, semaglutide and exercise are a dream team, if you will. While semaglutide helps manage hunger and blood sugar levels, exercise can work to reduce insulin sensitivity, accelerate weight loss, preserve muscle mass, improve cardiovascular health, and benefit your mental well-being. 

Even if you don’t hit the gym, it’s important to move your body every day. Generally speaking, you should aim for 30 minutes of moderate aerobic activity five days a week (and yes, walking counts). Start small, and go from there. Remember: consistency is key! 

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How can you get started on your weight loss journey?

Fortunately, all bodies are good bodies, and there is no one ‘right’ way to achieve your health and fitness goals. Rather, the focus seems to be shifting to a more holistic approach, incorporating a nutrient-dense diet, regular exercise, and, for some, that includes compounded GLP-1 injections or oral weight-loss medications. 

The good news is that Hers now conveniently provides a complete online platform where you can work with licensed healthcare providers to come up with the perfect multi-pronged weight-loss program for you. 

Here’s what to expect: Through Hers’ doctor-developed weight loss program, you will answer questions about your health history, lifestyle, and goals entirely online. A healthcare provider will then review your individual answers to come up with a well-rounded approach for your weight loss journey.

Unlike other weight loss programs, Hers considers underlying factors that might affect your weight and offers a personalized treatment plan based on your body and health history. Their comprehensive support includes medical advice, nutrition, daily movement, consistent sleep, and, if deemed appropriate for your journey, customized weight loss medications. 

Compounded semaglutides, or compounded GLP-1 injections, are now part of Hers’ product offerings.* About 1 in 3 adults achieved 20% weight loss while taking semaglutides. Possibly even more promising is that while taking a semaglutide, people not only lose weight but keep it off.

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Optimal health is possible with Hers

Finding the perfect plan to achieve your weight loss goals can be challenging, but you don’t have to do it alone. Hers is here to help you achieve your goal of optimal health from the comfort of your own home so you can live your best life on your terms. 

DISCLAIMER (1): Source link. In a study of 1,961 non-diabetic, obese or overweight adults with weight-related medical problems, 30% of participants prescribed Wegovy® lost 20% or more weight vs. 2% of the placebo group. Participants prescribed a reduced-calorie diet, increased physical activity, and monthly nutritional counseling. Novo Nordisk oversaw, designed, and sponsored the study.

DISCLAIMER (2): Source link. According to a study of 803 non-diabetic, obese or overweight adults with weight related medical problems, after 20 weeks, some people continued to take Wegovy®, while others switched to placebo. The treatment group continued to lose an average of 8% of body weight while the placebo group saw a 7% gain. Participants prescribed a reduced-calorie diet, increased physical activity, and monthly nutritional counseling. Novo Nordisk oversaw, designed, and sponsored the study. 

*Compounded semaglutide is not approved nor evaluated for safety, effectiveness, or quality by FDA. Not available in all 50 states. Weight Loss by Hims is a holistic program that includes nutrition support, technological tools, and compounded GLP-1s or medication kits including customized compounded medications prescribed based on what your provider determines is medically appropriate and necessary for you. See website for full details, important safety information, and restrictions, including online provider consultation requirements.


Brighid Flynn is a freelance writer based in Philadelphia where she lives with her husband, dog, and two little ones. 

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